Ephesians 4:17

So this I say, and solemnly affirm together with the Lord (as in His presence), that you must no longer live as the (unbelieving) Gentiles live, in the futility of their minds (and in the foolishness and emptiness of their souls),

Our minds and our spirits war against each other for control of our lives.  The spirit knows infinitely more and is in contact with the Holy Spirit.  The mind knows the reason, the five senses, and is limited.  God wants us to strive to trust in His leading over our mind.  The wisdom of God is limitless and a vital source for our lives to thrive.