Deuteronomy 28:45
So all these curses will come on you and pursue you and overtake you until you are destroyed, because you would not obey the voice of the Lord your God by keeping His commandments and His statutes which He has commanded you.

When we reject God and make ourselves into gods by following vain philosophies, we will open the door to destruction. If we don’t follow the commandments and statutes that God has given us in the Bible, we will allow the curse to be active in our lives. It comes down to keeping the faith focused on God and His Word and obeying the voice of the Lord.