Psalm 32:8-9

I will instruct you and teach you in the way you should go; I will counsel you (who are willing to learn) with My eye upon you. Do not be like the horse or like the mule which has no understanding, whose trapping includes bridle and rein to hold them in check, otherwise they will not come near to you.  

Our lives are not insignificant when the God of all offers to instruct us how we should go. We are important to God, and our lives have value and substance. We must be willing to learn and lay down any pride, fear, and doubt toward God. It is our choice to be led by God and our intention to learn.