Ephesians 1:18

And (I pray) that the eyes of your heart may be enlightened (flooded with the light of the Holy Spirit), so that you will know and cherish the hope (the divine guarantee, the confident expectation) to which He has called you, the riches of His glorious inheritance of the saints.

We can pray to God for understanding, wisdom, and guidance. As we draw nearer to God with our study of the word, we can be enlightened through the scriptures. The Holy Spirit will speak to us and guide us through our spirits. When we pray to have our hearts enlightened, we can gain a stronger relationship with God, and He hears and answers our prayers.